Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

Every multicellular organism, from tiny worms to humans, elephants, and whales, needs a way for their cells to connect with each other to form tissues, organs, and organize their overall body plan.

In the lab, it's easier to grow simple balls of cells than complex asymmetrical structures with two distinct ends—like the one million filtering units—nephrons—that make up a human kidney. But new ...

AMES, Iowa – A decade ago, Raquel Espin Palazon discovered that inflammatory signaling pathways must switch on for embryos to produce blood stem cells. The latest work from her lab shows the potential ...

The new €3.2M (US$3.7M) research lab will investigate immunogenic cell death mechanisms in lung cancer to improve how existing therapies trigger immune response.

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

[button url="http://chem.colorado.edu/" color="blue"]Department of Chemistry and Biochemistry[/button] [button url="www.colorado.edu" color="blue"]University of ...

Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a malignancy that often develops in a chronically inflamed milieu . Here, tumour ...

Researchers show that pharmacological activation of hypoxia signaling improves metabolism, limits fat accumulation, and ...