Inhibition of p53 rescues facial defects in a mouse model of an inherited craniofacial syndrome, Treacher Collins (pages 125–133). Craniofacial abnormalities comprise approximately one-third of all ...

Craniofacial abnormalities are some of the most common birth defects, ranging from cleft lips and palates to more severe disorders such as DiGeorge or Treacher-Collins syndromes. Craniofacial ...

Cleft lip and palate are the most common craniofacial birth defects in humans, affecting more than 175,000 newborns around the world each year. Yet despite decades of research, it’s still not known ...

Craniofacial abnormalities account for about one-third of all human congenital defects, but our understanding of the genetic mechanisms governing craniofacial development is incomplete. We show that ...

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial ...

Researchers have uncovered genetic elements that drive the rapid development of marsupials’ facial features. The study in fat-tailed dunnarts, native to Australia, is published today in eLife as the ...

Mice with targeted deletions of Apaf1 exhibit embryonic lethality and morphological defects, highlighting the pivotal role of this protein in apoptosis during mammalian embryogenesis. 18, 19 Loss of ...

Lead researcher Z. Zhang will hold an oral presentation on a study titled Fuz is Essential for Craniofacial and Tooth Development during the 89th General Session & Exhibition Lead researcher Z. Zhang ...

Developmental & Stem Cell Biology has become a crucial field for the understanding of tissue regeneration and implementation of regenerative medicine. The ability to repair or regenerate tissue is a ...

Some substances in medicines, household items and the environment are known to affect prenatal child development. Researchers tested the effects of five drugs (including caffeine and the blood thinner ...