Learn more about a new experimental procedure that uses cancer cells’ DNA repair system against itself to make drug-resistant ...

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a ...

Cancer cells survive by repairing damage to their DNA—even damage that would normally be fatal. One of their most important ...

Everyday DNA mutations can help us understand immune function and aging—and even mitigate harm caused by some inherited ...

Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.

An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved ...

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment ...

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer This was a prospective, cross-sectional, ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...