A Snakemake-based pipeline called Pipeasm automates key steps of genome assembly, from raw read trimming through scaffolding and contamination screening, and the authors report up to 99.6% BUSCO ...

In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models, or cultured cells.

Although it is an important technology for studying genomes, DNA sequencing was initially accomplished in 1977 by Frederick Sanger. Since its conception, the technology has developed rapidly. Alvaro G ...

This image compares three DNA sequencing technologies: Sanger sequencing, Massively Parallel DNA sequencing, and Nanopore DNA sequencing. Sanger sequencing (left) sequences 500-700 bases per reaction ...