Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, ...

Al-Aly is a physician and researcher at Washington University in St. Louis and chief of research at the VA Saint Louis Health Care System. At a dinner party recently, someone poured my friend a glass ...

Ziyad Al-Aly receives funding from U.S. Department of Veterans Affairs. A patient of mine, a veteran who had tried to quit smoking for over a decade, told me that after he started a GLP-1 drug for his ...