Main outcome measures Cumulative time dependent intake of preservatives, including those in industrial food brands, assessed ...

Background Exercise stress echocardiography (ESE) is widely used to detect inducible myocardial ischaemia. However, a substantial proportion of ESEs remains inconclusive or shows abnormal ...

After controlling for familial factors, acid-suppressive medications in pregnancy showed no association with risk for ...

Background Insomnia symptoms are prevalent in older adults and linked to cardiovascular disease (CVD), but the role of long-term symptom trajectories remains unclear. We investigated associations ...

The Framingham Heart Study identified key cardiovascular risk factors and developed the Framingham risk score, significantly impacting preventive cardiology. Future research in Framingham includes ...

Objective Physical activity (PA) is associated with a decreased incidence of dementia, but much of the evidence comes from short follow-ups prone to reverse causation. This meta-analysis investigates ...

Objective To examine and summarise evidence from meta-analyses of cohort studies that evaluated the predictive associations between baseline cardiorespiratory fitness (CRF) and health outcomes among ...

Investigators sought to determine whether alcohol intake, particularly at higher frequency or greater quantity, was consistently associated with elevated risk for cancer.