This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...
Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...
Photograph of offspring born to iron chelator-treated mothers during pregnancy. Left, normally developed XY male animal; middle, intersex-phenotype XY animal; right; completely feminized XY animal.
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Cellular crowding in fruit fly embryos triggers a critical DNA reorganization, biologists find
After fertilization, embryos race through rapid cell divisions before slowing down to build specialized cells that will carry out distinct functions in the developing body—but the signals that trigger ...
In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...
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