Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most ...

Respiratory infections are among the leading causes of illness and death in the elderly, driven by immune aging, chronic ...

Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also ...

An international research team led by Baylor College of Medicine and The University of Osaka have found a way to resume sperm production, leading to healthy offspring in mouse models with ...