Cholesterol enhances melanoma cell invasion by making nuclei squishier, revealing a potential treatment target in cancer progression.

Within a cell, the nucleus is surrounded by the nuclear envelope—two layers of phospholipid membrane that prevents the nucleus mixing with other parts of the cell, thus protecting the cell's DNA from ...

A team of Yale researchers discovered how a protein called Ndc1 coordinates nuclear pore and envelope assembly after cell division, an important component of understanding how cell nuclei change in ...

A new study published in the journal Developmental Cell has revealed how a cell nucleus can repair itself when ruptured to prevent DNA spilling out into the rest of the cell. A cell's nucleus has a ...

Every time a cell divides, the protective envelope that surrounds the nucleus is broken down and rebuilt into two new ones. Envelopes are highly complex structures of membranes and proteins which must ...

Expansion microscopy reveals the structure of huntingtin aggregates inside the cell nucleus. Huntington’s disease is a devastating neurogenerative disorder caused by a mutation in the HTT gene that ...

In a recent landmark study, scientists have unveiled how HIV-1 penetrates the cell's nuclear barrier—a discovery that could reshape antiviral strategies. The research, led by Professor Peijun Zhang, ...

Scientists at the Utrecht University in the Netherlands say they have identified a new way in which the toxic protein aggregates associated with Huntington’s disease may damage nerve cells and cause ...