Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's ...

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ossificans progressiva (FOP), Mrep functions as a pathogenic cell that ...

A literature search was carried out using PubMed and the keywords—osteogenesis; VEGF; endochondral ossification; and intramembranous ossification. Articles that only described the effect of VEGF on ...

Heterotopic ossification happens when bone grows outside of its normal location and into the surrounding soft tissues of your body. When this happens, the pieces of bone that develop are called ...

A man who visited hospital to get his knee checked out shocked doctors, who discovered his penis had started turning to bone. The unnamed 63-year-old man fell over on the sidewalk and hurt his knee, ...