Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

A research team affiliated with UNIST has made a significant discovery explaining why liver cancers associated with obesity and metabolic disorders tend to be more aggressive and less responsive to ...

New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better ...

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have ...

The CXCR6/CXCL16 signalling axis represents a pivotal mediator in the intricate interplay between immune responses, tumour progression and vascular pathology. CXCL16 exists both as a membrane-bound ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well ...

A triple drug approach that blocks the KRAS pathway at three points eliminated pancreatic tumors and prevented resistance in ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...