A large epidemiological study of more than 600,000 veterans with diabetes suggests GLP-1 weight-loss medications may reduce drug- and alcohol-related overdoses and deaths ...

Exenatide (Ex-4), a glucagonlike peptide-1 (GLP-1) receptor agonist currently used in the management of type 2 diabetes, could effectively treat drug addiction, including cocaine dependence, new ...

People taking GLP-1 drugs often talk about “food noise” vanishing: the constant mental chatter about food that dominated thei ...

Drugs commonly prescribed for weight loss and diabetes may offer unexpected benefits in tackling substance abuse, according ...

Weight-loss jabs could prevent and treat addiction to alcohol, cigarettes and drugs, according to a large study. Experts believe the way the medicines work on the brain’s reward pathway cuts cravings ...

People struggling with many addictions, ranging from opioids to gambling, are reporting similar experiences in clinics, on ...

Millions of people in the United States suffer from drug addictions. 1 “There's a lot of stigma related to addiction,” said Francesca Telese, a neuroscientist at the University of California, San ...

Dr. Nora Volkow, who leads the National Institutes of Drug Abuse, would like the public to know things are getting better. Mostly. By Matt Richtel Historically speaking, it’s not a bad time to be the ...

Astrocytic GLUR5 and dopamine D1 signaling. Illustration showing that astrocytically expressed GLUR5 and dopamine D1R and their coupled Ca 2+ signaling triggers the release of astrocytic factors (e.g.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.