Addiction to a drug means you cannot control your use of the substance, resulting in a harmful outcome. Drugs that are most commonly misused include alcohol, which can cause brain shrinkage, and ...

A large epidemiological study of more than 600,000 veterans with diabetes suggests GLP-1 weight-loss medications may reduce drug- and alcohol-related overdoses and deaths ...

Exenatide (Ex-4), a glucagonlike peptide-1 (GLP-1) receptor agonist currently used in the management of type 2 diabetes, could effectively treat drug addiction, including cocaine dependence, new ...

Astrocytic GLUR5 and dopamine D1 signaling. Illustration showing that astrocytically expressed GLUR5 and dopamine D1R and their coupled Ca 2+ signaling triggers the release of astrocytic factors (e.g.

This chapter was produced by a team of researchers: Maxineanu, I., Roop,S., Morris, S., McManus, S., Roberts, E., Strang, J. (2025) Drug use and dependence. In Morris ...