Click reactions—the subject of the 2022 Nobel Prize in Chemistry—come in many forms, but they all share a few key features. Namely, click chemistry forges new chemical bonds quickly, selectively, and ...

It has been almost a quarter-century since K. Barry Sharpless, M.G. Finn, and Hartmuth C. Kolb published the paper that some refer to as the click manifesto. In it, the researchers presented a vision ...

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...

The proposed platform for triple click chemistry has three functional groups that can be independently targeted for replacement by choosing an appropriate reaction partner. This platform is compatible ...

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...

Coined by Carolyn Bertozzi who won the 2022 Nobel prize for click chemistry, ‘bioorthogonal click chemistry’ encompasses a class of click reactions that are both fast and biologically inert, making ...

Chemotherapy, although lifesaving, causes a lot of side effects as it travels through the body to reach a cancerous tumor. From nausea to hair loss, these reactions arise because these drugs also ...

Researchers unveil a groundbreaking chemical reaction for efficient drug development and protein science by manipulating ...

A team of chemists has demonstrated a way to form sulfur-sulfur bonds at room temperature without any external catalyst, ...

Triple click chemistry has revolutionized chemical synthesis with its simplicity and efficiency, allowing for the quick and selective assembly of complex molecules. Now, in a recent study, researchers ...