Iptacopan is an innovative, first-in-class oral small molecule that reversibly inhibits factor B—a crucial serine protease in the alternative pathway of the complement system. By targeting this point ...

Complement is a subsystem of immunity that's fast acting and disregulated in multiple inflammatory diseases. Inhibition of complement is a young niche that's gonna get lots more attention soon.

The complement system maintains tissue homeostasis and integrity and forms the first central and immediately acting line of defence against invading infectious microorganisms. Complement activation ...