The field of immunology of ageing is rapidly evolving, with T cells playing a pivotal role in maintaining immune competence and overall organismal ...

Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing ...

Your skin is in a constant state of reinvention. Every month, your body sheds and regenerates its entire outer layer—a ...

Mucosal surfaces serve as critical battlegrounds where the immune system must balance tolerance to commensal organisms with rapid defense against pathogens.

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

One of the main changes is a loss of the innate immune system's naive T cells, the first line of defense against pathogens, and an increase in the adaptive immune system's memory T cells. This ...

Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage ...

Detectives often find important clues by digging through rubbish. That approach paid off tremendously for systems biologist Yifat Merbl. When she and her team investigated cellular recycling centres ...

Ribosomes don’t just make proteins—they can sense when something’s wrong. When they collide, they send out stress signals that activate a molecule called ZAK. Researchers uncovered how ZAK recognizes ...

A new scientific review reveals the molecular networks underlying coffee’s most potent compounds, demonstrating how this everyday drink may reduce disease risks through its coordinated antioxidant, ...