Explore essential statistical strategies for accurate protein quantification and differential expression analysis.

Heightened immune response to flagellins in commensal gut microbes predicted future CD in healthy first-degree relatives of patients.

Background Monogenic disorders are a major cause of fetal structural anomalies. Most genetic diagnoses involve de novo, biallelic or X linked variants; however, inherited variants in autosomal ...

The new funding will help the cluster build on initial milestones and to prepare for clinical applications, particularly in cancer.

Yonsei University researchers have developed a system for combining the benefits of planar array platforms with those of ...

Background Balanced translocation (BT) carriers have a high risk of recurrent miscarriage and abnormal offspring due to unbalanced gamete production. Clinical genetic testing often fails to detect BTs ...

Large protein machines in the body carry out many of the cell's most essential tasks, from energy production to the ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Scientists have uncovered a crucial weakness in the malaria parasite that could open the door to new treatments. Researchers identified a protein called Aurora-related kinase 1 (ARK1) that acts like a ...

Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, ...

Neurodegenerative disorders such as Alzheimer's disease (AD) are typically diagnosed after irreversible pathology has developed. Aging, the strongest risk factor, drives molecular changes that ...