Observational analyses can complement randomized clinical trial findings for the study of HPV vaccine effectiveness

Led by researchers at NDORMS as part of the Data Analysis and Real World Interrogation Network (DARWIN EU) initiative, a new ...
The New England Journal of Medicine

Prehospital Whole Blood in Traumatic Hemorrhage — a Randomized Controlled Trial

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...
Medscape

MRI-Guided TULSA Shows Faster Recovery Than Robotic Prostatectomy in CAPTAIN Trial

The CAPTAIN trial shows faster recovery, fewer complications, and better early function with the minimally invasive therapy ...
BMJ

Melatonin and melatonin agonists as antidepressants in the elderly: protocol for a systematic review and meta-analysis of randomised control trials

Introduction Depression and depressive symptoms are common in the elderly population and contribute to a lower quality of life. One change that is common in depression is the disruption of circadian ...
The Lancet

Neoadjuvant chemoradiotherapy followed by active surveillance versus standard surgery for oesophageal cancer (SANO trial): a multicentre, stepped-wedge, cluster-randomised, non ...

aDepartment of Surgery, Erasmus MC Cancer Institute, University Medical Centre, Rotterdam, Netherlands bDepartment of Pathology, Erasmus MC Cancer Institute, University Medical Centre, Rotterdam, ...
The Lancet

Combined mind–body physical exercise, cognitive training, and nurse-led risk factor modification to enhance cognition among older adults with mild cognitive impairment in ...

aJockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China bDepartment of Psychiatry, The Chinese University of Hong ...
BMJ

Building HPV vaccine confidence through codesigned interventions with and for healthcare workers in Nigeria: protocol for a pilot cluster randomised controlled trial

Introduction The human papillomavirus (HPV) vaccine can effectively prevent cervical cancer, yet HPV vaccine uptake is particularly low in some low-income settings, due to supply and vaccine ...