The field of spatial governance is undergoing profound change with the rise of digital technologies and artificial intelligence (AI). Traditionally, public ...

Effective anti-tumor immunity is not only defined by which immune cells are present in a tumor, but also by how they are organized in space. Across cancer ...

Contributed by Howard Y. Chang; received November 19, 2024; accepted February 20, 2025; reviewed by Jellert Gaublomme and David A. Quigley The spatial organization of cells within tissues plays a ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

In this GEN Learning Lab, our expert panelists Linda Orzolek, MS, MB, Xuhuai Ji, MD, PhD, and Christina Chang, PhD, will discuss the current landscape of imaging- and next-generation sequencing-based ...

More than half of patients with ischemic stroke experience futile reperfusion, increasing the risk of death and disabilities despite a successful recanalization. The reason behind this is debated, and ...

Abstract: As artificial intelligence (AI) advances, 3-D spatial computing has emerged as a key application in various fields. It interprets the 3-D space surrounding users and provides them with ...

Researchers at Atrium Health Wake Forest Baptist have shown that engineered macrophages can infiltrate brain tumor sites, recognize cancer cells, and destroy them in preclinical mouse models, ...

An effective and efficient method for joint analyses of multiple spatial transcriptomics datasets. We develop INSPIRE, a deep learning-based method for integrating and interpreting multiple spatial ...

Advancements in spatial perturbation transcriptomics (SPT) have revolutionized our understanding of cellular behavior in native tissue contexts by integrating spatial and perturbation data. However, ...