A new study has uncovered that a molecule called P-selectin plays a central role in regulating how blood stem cells age and respond to inflammation. Researchers found that as hematopoietic stem cells ...

Department of Pathology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an 710061, PR China Department of Nephrology, the Second Affiliated Hospital, Xi’an ...

Investigating clinical associations between genomic alterations and prostate cancer lineage states using circulating tumor cell RNA sequencing. This is an ASCO Meeting Abstract from the 2025 ASCO ...

GlycoMimetics. has been granted a patent for methods and compositions utilizing E-selectin antagonists, including glycomimetic compounds, to treat cancers such as leukemia, lymphoma, and myeloma. The ...

GlycoMimetics has been granted a patent for methods and compositions using E-selectin antagonists for treating and preventing cancers, metastasis, and thrombus formation. The patent includes ...

Background There is an urgent need to identify novel biomarkers for lupus nephritis (LN) in disease diagnosis, assessment, monitoring, and prognosis prediction. Here, we report a new non-invasive ...

The notion of taking aim at the galectin pathway across varied therapeutic areas has gained major traction in recent years, with a handful of companies drawing Wall Street’s interest as efforts plow ...

Brian A. Jonas, MD, PhD, discusses novel biomarkers being explored in acute myeloid leukemia, including e-selectin, which Jonas believes is very promising. Brian A. Jonas, MD, PhD, associate professor ...

Investigators are seeking to overcome barriers to help patients with acute myeloid leukemia achieve complete and durable remissions by focusing their attention on novel agents engineered to target ...

1 Division of Vascular Surgery, DeWitt-Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, United States 2 Vascular Biology Institute, University of Miami ...

Antiretroviral therapy (ART), which is a life-long therapeutic option, remains the only currently effective clinical method to treat HIV-1 infection. However, ART may be toxic to vital organs ...