The functioning of neurons, cells that transmit information in the nervous system, heavily relies on the production of ...

Researchers at the John Innes Centre and the Earlham Institute are pioneering powerful single-cell visualisation techniques ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Introduction: High levels of extracellular adenosine, highly abundant in the tumor microenvironment, promote immune suppression mainly through the A2AR expressed by tumor-infiltrating immune cells.

Abstract: Deciphering cell-type composition is critical for charting single-cell spatial maps and cellular atlases of organisms. Most Spatial Transcriptomics (ST) data lack single-cell resolution, ...

In their study, Avraham-Davidi et al. combined scRNA-seq and spatial mapping studies to profile two preclinical mouse models of colorectal cancer: Apcfl/fl VilincreERT2 (AV) and Apcfl/fl LSL-KrasG12D ...

Hi, I am trying to run sopa Baysor cell segmentation pipeline with 10x xenium data. I am using snakemake version 9.14.0, and sopa newest version. When i run ...

Vascular smooth muscle cells and pericytes are mural cells that maintain the integrity and support the function of blood vessels. The molecular mechanism underlying the specification of pericytes and ...