Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental ...

This project implements a complete deep learning pipeline for counting cells in microscopy images using semantic segmentation. Given fluorescence microscopy images, the model predicts a binary ...

ABSTRACT: Spatial transcriptomics is undergoing rapid advancements and iterations. It is a beneficial tool to significantly enhance our understanding of tissue organization and relationships between ...

Cytotoxicity is a broad term that refers to the negative effects of chemical or environmental changes on cell health. Cells exposed to a cytotoxic stimulus may lose metabolic activity, experience ...

Exploring biology in its native environment is perhaps the ideal scenario for generating better hypotheses about the cellular interactions that influence—and drive—healthy and diseased states, ...

Formalin-fixed, paraffin-embedded (FFPE) tissues represent the predominant sample conservation method in clinical practice, yet degraded and crosslinked RNA has long limited whole-transcriptome ...

Cell segmentation is a crucial step in numerous biomedical imaging endeavors—so much so that the community is flooded with publicly available, state-of-the-art segmentation techniques ready for out-of ...

10x released a new version of Spaceranger earlier this month. They now offer cell segmentation. How should I load the data into Seurat? I believe it is similar to Vizgen, where you have the cell ...