The SOFA-2 score included new definitions, new variables, and revised thresholds to categorize the severity of organ dysfunction in critical illness. The updates reflected changes in practice, ...

In a recent study investigating the effects of prostaglandin E1 (PGE1) on reducing inspired oxygen concentration during one-lung ventilation (OLV), several key findings and outcomes were identified.

Acute respiratory distress syndrome is a significant complication in critical care patients. COVID-19 (C19)-associated severe respiratory failure is related to it, and d-dimer rise predicts a worse ...

We present a case of a man in his early 50s, who developed severe respiratory distress following exposure to airbag fumes after a road traffic accident. Despite initial treatment for lower respiratory ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

The following is a summary of “Prognostic value of PaO2/FiO2 ratio in predicting clinical outcomes in COVID-19 patients,” published in the June 2024 issue of Critical Care by Canto-Costal et al.

The models use maximal deflection of esophageal pressure to quantify HFOT-related breathing effort (ΔPes) and the risk for strong breathing effort (ΔPes >10 cmH2O). Two models have been developed to ...

Introduction The use of fibrinolytic therapy has been proposed in severe acute respiratory distress syndrome (ARDS). During the COVID-19 pandemic, anticoagulation has received special attention due to ...

Correspondence to Dr David G Sweet, Neonatal Unit, Royal Maternity Hospital, Belfast, Belfast, UK; david.sweet{at}belfasttrust.hscni.net What should neonatologists do now, while acknowledging that we ...

ABSTRACT: Background: Recombinant human soluble thrombomodulin (rhTM) was approved for the treatment of disseminated intravascular coagulation in Japan, and rhTM has anti-inflammatory effects.

The PF ratio (PaO2/FiO2 ratio) is an essential indicator used in medicine to gauge the severity of a patient’s hypoxemic respiratory failure. This value helps healthcare professionals determine ...