CYP2D6, a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the body.

Nov 13, 2025 · Complete information for CYP2D6 gene (Protein Coding), Cytochrome P450 Family 2 Subfamily D Member 6 (Gene/Pseudogene), including: function, proteins, disorders, pathways, …

Oct 28, 2020 · CYP2D6 is defined as a gene that encodes an enzyme involved in drug metabolism, with specific alleles, such as CYP2D6∗7, characterized by variants that can lead to nonfunctional protein …

Jun 23, 2025 · CYP2D6 is responsible for the metabolism of approximately 20-25% of all clinically used drugs. The chemical reactions it catalyzes in the liver make substances easier for the body to eliminate.

Oct 7, 2024 · Among the members of the family, the 2D6 isoform is the most extensively investigated one. Having a highly polymorphic nature, with remarkable inter-individual and inter-ethnic …

CYP2D6 is part of the cytochrome P450 family of enzymes that helps the body break down certain medicines. A pharmacogenomic test can help your medical team know how well your CYP2D6 …

CYP2D6 encodes a cytochrome P450 enzyme that metabolises about 20% of commonly prescribed medicines. Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) is an important gene in the …

We recently tested you for the CYP2D6 gene. This info sheet explains the test, your results, and what your doctor may do with that information. Genes are pieces of DNA that provide instructions to make …

Apr 7, 2024 · The CYP2D6 gene is a critical component of drug metabolism and plays a significant role in the field of pharmacogenomics. This gene is responsible for breaking down medications like …

Genetic differences in cytochrome P450 (CYP)-mediated metabolism have been known for several decades. The clinically most important polymorphic CYP enzyme is CYP2D6, which plays a key role …