Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4 gene.

The CYP3A4 enzyme is a significant member of the cytochrome P450 (CYP) family. This enzyme is primarily found in the liver and intestines, where it plays a role in processing various substances that …

CYP3A, a key member of the cytochrome P450 (CYP450) superfamily, is integral to drug metabolism, processing a substantial portion of medications. Their role in drug metabolism is particularly …

CYP3A4 CYP3A4 is the isozyme that metabolizes the most drugs. Genetic testing has identified approximately 20 different variants and nearly 350 SNPs of the CYP3A4 gene. Polymorphisms in …

Feb 27, 2025 · CYP3A4 is a key enzyme responsible for metabolizing a broad range of medications from many different therapeutic categories. This enzyme's activity significantly impacts drug efficacy …

Nov 13, 2025 · CYP3A4 (Cytochrome P450 Family 3 Subfamily A Member 4) is a Protein Coding gene. Diseases associated with CYP3A4 include Vitamin D-Dependent Rickets, Type 3and Major …

Sep 9, 2025 · Gene target information for CYP3A4 - cytochrome P450 family 3 subfamily A member 4 (human). Find diseases associated with this biological target and compounds tested against it in …

Jun 16, 2025 · Cytochrome P450 3A4, or CYP3A4, is an enzyme from the larger cytochrome P450 superfamily, a group of proteins that process various substances. Think of CYP3A4 as a biological …

Apr 10, 2025 · These findings demonstrate the feasibility to selectively inhibit CYP3A4 and provide guidance for designing better CYP3A4 selective inhibitors.

Jan 1, 2024 · CYP3A4 aids in detoxifying bile acids, ceasing steroid hormone action, and removing phytochemicals in food and most medications. Glucocorticoids and other pharmacological medicines …