This article explores basic statistical concepts of clinical trial design and diagnostic testing, or how one starts with a question, formulates it into a hypothesis on which a clinical trial is then built, and …

Hypothesis testing is a fundamental statistical technique used in clinical research to evaluate the validity of hypotheses about a population based on sample data. This section provides an in-depth …

Hypothesis testing and its emphasis on p values and significance may be replaced by or comple-mented with other methods of reporting clinical trials, but it currently remains the most widely used method of …

Jul 3, 2025 · Q: What is hypothesis testing in clinical trials? A: Hypothesis testing in clinical trials is a statistical procedure used to determine whether a new treatment is effective and safe compared to …

Aug 11, 2025 · A common question to be addressed in clinical research, and in scientific research in general, is "what constitutes proof?" How do we decide when the evidence for or against a …

Discover everything you need to know about sample size and hypothesis testing for clinical trials.

Jun 1, 2025 · Hypothesis testing evaluates the evidence for treatment effects, often using statistical tests such as t-tests, analysis of variance or chi-squared tests, while confidence intervals quantify the …

P values and hypothesis testing methods are frequently misused in clinical research. Much of this misuse appears to be owing to the widespread, mistaken belief that they provide simple, reliable, and …

Nov 1, 2025 · Crafting a research hypothesis involves several key steps. First, conduct a comprehensive literature review to identify a knowledge gap in your field. Once a relevant question or problem is …

Confidence intervals and hypothesis tests rely on Student's t-distribution to cope with uncertainty resulting from estimating the standard deviation from a sample, whereas if the population standard …