Ligation is the joining of two nucleotides, or two nucleic acid fragments, into a single polymeric chain through the action of an enzyme known as a ligase.

Ligation is one of the crucial steps in gene cloning because the DNA ligase enzyme joins a DNA vector with the target gene sequence through their blunt or sticky ends.

Share Kids Definition ligation noun li· ga· tion lī-ˈgā-shən : the act of tying a bodily part (as a blood vessel) with a ligature

Aug 25, 2025 · Ligation refers to the fundamental process of binding, tying, or joining distinct components together. This concept applies across various scientific and medical disciplines. It …

Cells naturally carry out ligation during DNA replication, when the Okazaki fragments are joined together. Cells also use ligation to repair DNA that has been damaged, either by normal cell …

LIGATION definition: 1. the act of tying a blood vessel or other tube in the body with a piece of thread or wire: 2…. Learn more.

Definition of ligation noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

Ligation of DNA is a critical step in many modern molecular biology workflows. The sealing of nicks between adjacent residues of a single-strand break on a double-strand substrate and the joining of …

LIGATION definition: the act of ligating, especially of surgically tying up a bleeding artery. See examples of ligation used in a sentence.

DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in duplex DNA in …