Insulin resistance happens when your muscle, fat and liver cells don’t respond as they should to insulin, a hormone that regulates blood sugar.

May 15, 2024 · When your body is exposed to too much blood sugar over an extended period of time, you can develop insulin resistance. Here's what that means: A l ot of blood sugar enters …

Aug 20, 2025 · Insulin resistance develops when cells don’t respond effectively to insulin, prompting the pancreas to initially produce more insulin to maintain stable blood sugar, but …

Apr 22, 2024 · Experts still don't fully understand what causes insulin resistance and prediabetes. Things that can make this condition more likely include: Certain racial or ethnic backgrounds: …

People with insulin resistance, also known as impaired insulin sensitivity, have built up a tolerance to insulin, making the hormone less effective. As a result, more insulin is needed to persuade …

What Is the Main Cause of Insulin Resistance? The main causes of insulin resistance include obesity, a waist measurement of 40 inches or more for men and 35 inches or more for women, …

Jun 1, 2025 · What causes insulin resistance? Obesity (being significantly overweight and belly fat), an inactive lifestyle, and a diet high in carbohydrates are the primary causes of insulin …

Insulin resistance is a condition in which your body doesn’t respond to insulin the way it should. Insulin is a hormone made by your pancreas. Insulin resistance can lead to increased blood …

Sep 5, 2025 · Insulin resistance is a risk factor for the development of type 2 diabetes and heart disease. Common signs of insulin resistance include weight gain around the abdomen, fatigue, …

Nov 6, 2025 · The exact cause of insulin resistance is unknown but strongly linked to excess body weight and a sedentary lifestyle. Over time, insulin resistance can lead to prediabetes, a …